p53 polymorphism and p21 haplotype in the intestinal gastric cancer and the precancerous lesions
نویسندگان
چکیده
Ya-Guang Xi, Ke-Yue Ding, Xiu-Lan Su, Da-Fang Chen, Wei-Cheng You, Yan Shen and Yang Ke Beijing Institute for Cancer Research, School of Oncology, Peking University, Beijing, China, Chinese National Human Genome Center, Beijing, China, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences (CAMS) and Peking Union Medical College (PUMC), Beijing, China, Inner Mongolia Medical College, Huhhot, China and Department of Cell Biology and Human Genetics, Peking University, Beijing, China
منابع مشابه
ارزش بیومارکرهای معده ای در شناسایی ضایعات پیش سرطانی در بیماران دیس پپسی
Background and purpose: Identifying precancerous lesions for early detection of gastric cancer is greatly important in high risk areas for stomach cancer. In this study, we evaluated stomach biomarkers as a non-invasive method for recognition of gastric precancerous lesions. Materials and methods: In a cross-sectional study, patients with chronic dyspeptic symptoms who were candidate for endos...
متن کاملAssociation of P53 (+16ins-Arg) Haplotype with the Increased Susceptibility to Breast Cancer in Iranian-Azeri Women
Background:Many case-control investigations have showed the correlation of TP53 gene polymorphisms with the risk of breast cancer. However, the findings are not consistent. It has been suggested that the investigation of P53 genotype combinations and haplotypes may be more helpful than the detection of single polymorphisms. In the present study, we investigate...
متن کاملStudy of Association Between TLR4 D299G and T399I Polymorphisms and Risk of Gastric Cancer
Introduction:Gastrointestinal cancers constitute more than one-third of the most common cancers and half of the fatal cancers worldwide. Toll-like receptors (TLRs) are identified as pivotal receptors in innate immunity responses. TLR4 is the main receptor that plays a role in lipopolysaccharide (LPS) sensing of gram-positive bacteria. D299G (rs4986790)&...
متن کاملبررسی بیان پروتئین های p53 و HER2 با عوامل مرتبط با پیش آگهی کارسینوم معده به روش ایمونوهیستوشیمی
Background and purpose: Gastric carcinoma is one of the most common malignancies and its early diagnosis can be effective in the treatment method and the rate of the patients’ survival. Ïn the past recent years, many genes have been identified which may have relationship with the prognosis of this disease and the patient’s survival. This study is going to investigate the rate and pattern of p53...
متن کاملStudy of Association Between TLR4 D299G and T399I Polymorphisms and Risk of Gastric Cancer
Introduction:Gastrointestinal cancers constitute more than one-third of the most common cancers and half of the fatal cancers worldwide. Toll-like receptors (TLRs) are identified as pivotal receptors in innate immunity responses. TLR4 is the main receptor that plays a role in lipopolysaccharide (LPS) sensing of gram-positive bacteria. D299G (rs4986790)&...
متن کامل